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KMID : 0366220090440040261
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Korean Journal of Hematology
2009 Volume.44 No. 4 p.261 ~ p.267
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A Case Report of Helicobacter Pylori Negative Gastric MALT Lymphoma with Monoclonal Gammopathy
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Hwang Eui-Kyung
Jang Eun-Jung
Kim Sun-Mi
Jeong Seong-Hyun
Lee Hyun-Woo
Kang Seok-Yun
Choi Jin-Hyuk
Han Jae-Ho
Kim Jang-Hee
Kim Myung-Wook
Yoo Byung-Moo
Park Joon-Seong
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Abstract
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Lymphomas of mucosa-associated lymphoid tissue (MALT) comprise 7% of all newly diagnosed non-Hodgkin’s lymphomas. Helicobacter pylori (H. pylori) negative gastric MALT lymphomas account for 28 to 45% of gastric MALT lymphomas. H. pylori infection has a close relationship with most gastric low-grade B cell lymphomas of the MALT type. Monoclonal gammopathy can be seen in 36% of the patients and negatively associated with responses to eradication of H. pylori in gastric MALT lymphoma. Here, we describe a case of H. pylori negative MALT lymphoma that arose from the stomach with massive plasmacytic differentiation mimicking an extramedullary plasmacytoma with monoclonal gammopathy, and that was cured by total gastrectomy, chemotherapy and radiotherapy. (Korean J Hematol 2009;44:261-267.)
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KEYWORD
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Helicobacter pylori negative, Gastric B cell lymphoma of mucosa-associated lymphoid tissue type, Monoclonal gammopathy
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